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Year : 2017  |  Volume : 18  |  Issue : 3  |  Page : 185-189

Hypertensive uveitis: an initial presentation for primary antiphospholipid syndrome

1 Department of Ophthalmology, Kasr Al-Ainy School of Medicine, Faculty of Medicine, Cairo University, Giza, Egypt
2 Department of Rheumatology and Rehabilitation, Kasr Al-Ainy School of Medicine, Faculty of Medicine, Cairo University, Giza, Egypt

Correspondence Address:
Riham S.H.M Allam
4 Omar Ebn Alkhattab Street, Dokki, Giza 12311
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/DJO.DJO_4_17

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The authors aim to report a case of hypertensive uveitis-associated primary antiphospholipid antibody syndrome (APS). A 25-year-old woman presented with unilateral painless diminution of vision. Examination revealed right chronic anterior uveitis, complicated cataract, and appositional angle-closure glaucoma uncontrolled with medications, for which sequential phacoemulsification–trabeculectomy was performed. Rheumatological consultation revealed the diagnosis of primary APS according to revised Sapporo criteria. Accordingly, systemic steroids and hydroxychloroquine were prescribed. The patient experienced an attack of posterior uveitis 2 years later, which necessitated a maintenance dose of an immunomodulator. Following systemic treatment and intravitreal triamcinolone, the patient’s vision improved from hand motion good projection to 0.3 with no inflammation 8 months following the last relapse. We conclude that hypertensive uveitis can be a presenting feature of primary APS. Antiphospholipid laboratory profile could be added to the workup of uveitis whenever clinical suspicion is present. Thromboprophylaxis could be added when antiphospholipid is positive.

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