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ORIGINAL ARTICLE
Year : 2017  |  Volume : 18  |  Issue : 2  |  Page : 51-56

Oral linolenic acid dietary supplementation in posterior blepharitis and meibomian gland dysfunction


Department of Ophthalmology, Fayoum University, Fayoum, Egypt

Correspondence Address:
Ahmed T.S. Saif
Department of Ophthalmology, Fayoum University, 5 Sherif Street, Babel Louk Square, Fayoum, Cairo 11111
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1110-9173.208534

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Aim The aim of this research is to study the role of oral linolenic acid (omega-3 fatty acids) dietary supplementation in posterior blepharitis and meibomian gland dysfunction (MGD) in patients attending the Outpatient Clinic at Fayoum University Hospital. Patients and methods Fifty patients with moderate to severe chronic blepharitis and simple obstructive MGD were included in the study. Patients received oral omega-3 dietary supplementation consisting of one 1000-mg capsule once daily and were examined every 6 weeks for 3 months. Objective clinical measures included tear production (Schirmer I with anesthesia), tear film stability (fluorescein tear break-up time), ocular surface health (fluorescein surface staining), tear meniscus height, plugged meibomian gland orifices, and eyelid telangiectasia. Results Twenty-four (48%) patients had an age between 45 and 60 years, 20 (40%) patients were more than 60 years old, and six (12%) patients were less than 45 years old. The male to female ratio was 1 : 2. Twelve (24%) male patients were smokers, whereas four (8%) female patients were using oral contraceptive pills. Twenty-two (44%) patients were hypertensive, whereas eight (16%) patients were diabetic. There was a significant improvement of dry-eye symptoms, signs, tear break-up time, Schirmer test, and meibomian gland orifices after 3 months of oral linolenic acid use. Conclusion The results after 3 months of treatment and follow-up were very satisfactory for the efficacy. Oral linolenic acid (omega-3 fatty acids) is effective in the treatment of moderate to severe chronic blepharitis and MGD.


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